Born in Lawrence, Kansas in 1940 Clytie Alexander was educated in Quebec and Bangladesh where she studied music and dance. She later apprenticed with an architect and studied art at UCLA. She is the recipient of awards and grants that include the American Academy of Arts and Letters Art Purchase Award, 2003, 2007 and 2013; the Adolph and Esther Gottlieb Foundation Grant, 2005: the Pollock Krasner Foundation Grant, 1993 and 2001; and the Elizabeth Foundation for the Arts Grant 1998 and Studio Space Program 1998-2018. Her work can be seen in many private and public collections including the Museum of Contemporary Art, San Diego, CA; the Getty Research Institute Library, Los Angeles, CA; the Nelson-Atkins Museum of Art, Kansas City, MO; the Weatherspoon Art Museum, Greensboro, NC; the Los Angeles County Museum of Art: Fondo Francesco Moschini A.A.M. Architectura Arte Moderna, Rome Italy.
Clytie Alexander lives and works in New York and Los Angeles. Her work is represented by the Betty Cuningham Gallery New York.